Skip For Now
The maths doesn't work on Team Rocket's Mewtwo ex (Destined Rivals) right now. At $16.56 raw against $105.54 for a PSA 10, that works out to -1% ROG. Better to put the submission slot toward a stronger card from the same set.
Most grading maths asks you to guess your odds of a PSA 10 first. This works backwards from the prices instead and tells you what those odds would have to be.
The number is different on every card. It's how confident you'd need to be that this copy gems before grading pays for itself, so 20% means roughly a 1 in 5 shot and 50% means a coin flip.
Grade it if you rate your copy better than that, leave it raw if you don't.
It assumes a 9 is the worst you'll get. Centering and edge whitening send plenty of modern cards back at 8 or lower, and that's not priced in here, so treat this as the floor of the bar rather than the whole of it. Selling fees aren't counted either.
(cost - PSA 9) ÷ (PSA 10 - PSA 9)
Not worth grading at any odds
Even a guaranteed PSA 10 ($105.54) wouldn't cover your $106.56 cost (raw + grading + shipping).
A clean raw copy is worth more to you than a slabbed one here. Sell it as is, or keep it for the collection.
Among the 93 cards in Destined Rivals with PSA 10 sale data, Team Rocket's Mewtwo ex ranks 27th for Return on Grading and 27th by PSA 10 price. Of the 22 Ultra Rare cards with PSA 10 sales, it is 1st for Return on Grading. The median PSA 10 in this set sells for $57.91. 4 of the 93 clear a 100% Return on Grading.